Main » Infectious diseases » Infections Acquired through the Skin and Mucous Membranes » The systemic mycoses
Photo 1. Madura foot. This chronic and disabling condition may be caused by a wide variety of organisms ranging from Actinomycetes to various Fungi imperfecti.
Photo 2. X-ray of Madura foot. Infiltration of the tarsals and metatarsals occurs in late cases.
Photo 3. Serological diagnosis. Fungal species identification can be made serologically. This serum contains antibodies to Madurella mycetomae.
Photo 4. Culture diagnosis. M. mycetomae (4) and Streptomyces pellietieri (5) on Sabouraud medium show typically shaped and pigmented colonies.
Photo 5. Culture diagnosis (Streptomyces pellietieri).
Photo 6. Chronic maduromycosis due to S. somaliensis infection. Extensive sinus formation and osteitis have led to gross disfigurement in this Sudanese man.
Photo 7. Early chromoblastomycosis. The early lesions show a violet discoloration. The primary ulcer spreads slowly and is followed by verrucous lesions. Several species of fungi may cause the disease.
Photo 8. Verrucous dermatitis. This is the late stage of chromoblastomycosis. The lesions are very chronic, usually painless but irritating. Lymphoedema follows lymphatic stasis.
Photo 9. Lobos disease. This condition usually presenting with shiny, keloid-like lesions, produces a general picture similar to late chromoblastomycosis and occurs in the north east of Brazil. It is caused by Loboa Idboi.
Photo 10. Loboa loboi. The typical spores of this fungus are seen in this biopsy specimen from the keloidal lesions. (x350)
Photo 11. Mucocutaneous lesions in South American blastomycosis. Gross infiltration of mucocutaneous and mucous surfaces by Paracoccidioides brasiliensis may spread to the pharynx and larynx.
Photo 12. X-ray of chest in South american blastomycosis. Chronic pulmonary infiltration may result in fibrosis and eventual death from respiratory insufficiency.
Photo 13. Meningitis due to Cryptococcus neoformans. The organisms are readily visualised in Indian ink preparations of infected cerebrospinal fluid from patients with meningitic infection.
Photo 14. Lesions of sporotrichosis. The typical lymphatic spread with ulceration of secondary nodules is well shown in this figure of a patient seen in Belo Horizonte, Brazil.
Photo 15. African histoplasmosis. This type of histoplasmosis caused by Histoplasma duboisii commonly produces large destructive lesions of the skin and subcutaneous tissues. Bones are often involved in the invasive process.
Photo 16. H. duboisii in biopsy. The typical giant cell reaction to the presence of H. duboisii spores is seen in this figure. (x350)
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» The superficial mycoses
» The systemic mycoses