Main » Infectious diseases » Snail-mediated Helminthiases » Schistosoma japonicum
Schistosoma japonicum infection is a zoonosis. It is found in a wide variety of vertebrate hosts, including domestic animals and bovines. Human infection frequently occurs in farm workers.
Photo 1. Radio-isotope scan of patient with S. japonicum infection. Severe hepatic fibrosis and massive splenomegaly occur in S. japonicum infection, in the same manner as in S. mansoni (see 369), often with ascites. This Chinese patient was infected both with S. japonicum and Clonorchis sinensis.
Photo 2. Philippino boy with gross splenomegaly. Advanced lesions due to S. japonicum may be seen in children and adolescents.
Photo 3. Ova of S. japonicum in temporal lobe of human brain. Schistosomal lesions in the brain may contain large numbers of ova in necrotic material, often surrounded by eosinophils. (Little cellular reaction is seen in this figure.) (x 150)
Photo 4. Eggs of S. japonicum in wall of colon. The adult worms do not invade the vesical plexus, but usually inhabit the mesenteric plexus. The diagnosis of S. japonicum can usually be made by finding typical eggs in the faeces. However, it is commoner for eggs of S. japonicum to be deposited in ectopic sites than those of other schistosome species. (x 150)
Photo 5. Intradermal test. In any type of schistosomiasis the diagnosis may be suggested in the absence of demonstrable ova by the response to an intradermal injection of a suitable antigen. This figure shows a typical response to antigen prepared from S. mansoni.
Photo 6. Complement fixation test.
Serological diagnosis is of particular value in epidemiological surveys. (Row A is a negative control serum. Positive reactions to S. mansoni from patients' sera are row B (1/25), C, E (1/32), F, G (1/16). H is complement control. D is considered negative at 1/8.)
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» Schistosomes Found Uncommonly in Man
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